Division of Rheumatology

We are devoted to delivering the highest standard of clinical care to all with rheumatic diseases. We strive for excellence in clinical, teaching and research activities.

Head of Division Prof. Lai-Shan Tam, Professor
Academic Staff and Clinical Staff Prof. Edmund K Li, Clinical Professor (honorary)
Dr. Kong-Chiu Wong, Consultant
Dr. Priscilla CH Wong, Associate Consultant
Dr. Lydia HP Tam, Resident
Research Staff Dr. Martin Li
Isaac TH Cheng
Queenie WY Mak
Steven HM Lam
Xerox SL Lau
Michelle OY Pui
Nursing Staff Tena KY Li
Emily YM Leung
Tracey WK Yu

Research Interests

  • Inflammatory bone loss and steroid induced osteoporosis
  • Premature atherosclerosis in rheumatic disease patients

Selected Publications

  1. Tam LS, Chan AYK, Chan PKS, AR Chang, Li EK. Higher prevalence of squamous intraepithelial lesion in systemic lupus erythematosus - Association with human papillomavirus infection. Arthritis Rheum 2004;50:3619-3625.

  2. Tam LS, Li EK, Wong CK, Lam CW, Li WC, Szeto CC. Safety and efficacy of leflunomide in the treatment of lupus nephritis refractory or intolerant to traditional immunosuppressive therapy: An open label trial. Ann Rheum Dis 2006;65:417-8.

  3. Li EK, Tam LS, Wong CK, Li WC, Lam CW, Wachtel-Galor S, Benzie IFF, Bao YX, Leung PC, Tomlinson B. Safety and efficacy of ganoderma lucidum (lingzhi) and san miao san supplementation in patients with rheumatoid arthritis: A double-blind, randomized, placebo-controlled pilot trial. Arthritis Rheum 2007;57:1143-1150.

  4. Tam LS, Shang Q, Li EK; Tomlinson B, Chu T, Li M, Leung YY, Kwok LW, Wong KC, Li TK, Yu T, Zhu YE, Kun EW, Yip G, Yu CM. Subclinical carotid atherosclerosis in patients with psoriatic arthritis. Arthritis Rheum 2008; 59:1322–1331.

  5. Li EK, Zhu TY, Hung VY, Kwok AW, Lee VW, Lee KK, Griffith JF, Li M, Wong KC, Leung PC, Qin L and Tam LS. Ibandronate increases cortical bone density in patients with systemic lupus erythematosus on long-term glucocorticoid. Arthritis Res Ther 2010;12:R198 (22 October 2010).

  6. Tam LS, Gu J, Yu D. Pathogenesis of ankylosing spondylitis. Nat Rev Rheumatol 2010 2010 Jul;6(7):399-405.

  7. Tam LS, Li EK, Shang Q, Tomlinson B, Li M, Leung YY, Kuan WP, Kwok LW, Li TK, Zhu TY, Kun EW, Yip G, Yu CM. TNF-α blockade is associated with sustained regression of carotid intima-media thickness for patients with active psoriatic arthritis-a 2-year pilot study. Ann Rheum Dis 2011;70:705-706.

  8. Yu SL, Chan PK, Wong CK, Szeto CC, Ho SC, So K, Yu MM, Yim SF, Cheung TH, Wong MC, Cheung JL, Yeung AC, Li EK, Tam LS. Antagonist-mediated down-regulation of toll-like receptors increases the prevalence of human papillomavirus infection in systemic lupus erythematosus. Arthritis Res Ther 2012:18;14(2):R80.

  9. Tam LS, Shang Q, Li EK, Wong S, Li RJ, Lee KL, Leung YY, Ying KY, Yim CW, Emily W Kun, Leung MH, Li M, Li TK, Zhu TY, Chui RK, Tseung L, Yu SL, Kuan WP, Yu CM. Serum soluble receptor for advanced glycation end products levels and aortic augmentation index in early rheumatoid arthritis - A prospective study. Semin Arthritis Rheum 2013;42:333-45.

  10. Zhu TY, Griffith JF, Qin L, Hung VW, Fong TN, Au SK, Tang XL, Kwok AW, Leung PC, Li EK, Tam LS. Structure and strength of the distal radius in female patients with rheumatoid arthritis: A case-control study. J Bon Miner Res 2013;28:794-806.

  11. Zhu TY, Griffith JF, Qin L, Hung VW, Fong TN, Au SK, Li M, Lam YY, Wong CK, Kwok AW, Leung PC, Li EK, Tam LS. Alterations of bone density, microstructure, and strength of the distal radius in male patients with rheumatoid arthritis: a case-control study with HR-pQCT. J Bone Miner Res. 2014 Sep;29(9):2118-29. doi:10.1002/jbmr.2221.

  12. Tam LS, Shang Q, Kun EW, Lee KL, Yip ML, Li M, Li TK, Zhu TY, Pui MO, Li EK, Yu CM. The effects of Golimumab on subclinical atherosclerosis and arterial Stiffness in ankylosing spondylitis—a randomized, placebo-controlled pilot trial. Rheumatology (Oxford). 2014 Jun;53(6):1065-74.

  13. Shen J, Shang Q, Wong CK, Li EK, Wang S, Li RJ, Lee KL, Leung YY, Ying KY, Yim CW, Kun EW, Leung MH, Li M, Li TK, Zhu TY, Yu SL, Kuan WP, Yu CM, Tam LS. IL-33 and soluble ST2 levels as novel predictors for remission and progression of carotid plaque in early rheumatoid arthritis: A prospective study. Semin Arthritis Rheum. 2015 Aug;45(1):18-27. doi: 10.1016/j.semarthrit.2015.02.001. Epub 2015 Feb 20.

  14. Shen J, Shang Q, Li EK, Leung YY, Kun EW, Kwok LW, Li M, Li TK, Zhu TY, Yu CM, Tam LS. Cumulative inflammatory burden is independently associated with increased arterial stiffness in patients with psoriatic arthritis: a prospective study. Arthritis Res Ther. 2015 Mar 17;17:75. doi: 10.1186/s13075-015-0570-0.

  15. Shen J, Shang Q, Tam LS. Targeting inflammation in the prevention of cardiovascular disease in patients with inflammatory arthritis. Transl Res. 2016 Jan;167(1):138-51. doi: 10.1016/j.trsl.2015.05.006. Epub 2015 May 16. Review.