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| Division of Nephrology | |
| Head of Division: Professor Philip KT Li | |
| Members: | |
| Dr. Kai Ming Chow, Dr. Kwok-Yi Chung, Dr. Bonnie Ching-Ha Kwan, Dr. Chi Bon Leung, Dr. Siu Fai Lui, Dr. Cheuk Chun Szeto | |
| Graduate Student: | |
| Wang Gang | |
| Research Assistant: | |
| So Ying Ho, Ka Bik Lai, Peter Poon, Carol YK Szeto | |
| Research Interests: | |
Treatment of lupus nephritis using variours immunosuppressive regimens, immunology and immunogentics of glomerulonephritis, in particular lgA nephropathy, the optimal use of subcutaneous erythropoietin in dialysis patients in correction of anaemia, treatment of CAPD and transplant patients with dyslipidemia, treatment of CAPD peritonitis, the use of connectology in CAPD patients, rehabilitation status of dialysis patients. Another area of research has been on the biocompatibility of the current peritoneal dialysis solutions. Suppression of neutrophil superoxide anion formation, neutrophil oxygen consumption and intracellular pH are used to demonstrate the non-physiological aspect of different components of peritoneal dialysis solutions. Alternative components are currently sought and tested to improve the biocompatibiltiy of the solutions. The haemodynamics and urea kinetics of haemodialysis is also being studied, with the aim of improving the comfort, safely and adequacy of haemodialysis. |
|
| Selected Publications: | |
| 1. | Li PK, Law MC, Chow KM, Chan WK, Szeto CC, Cheng YL, Wong TY, Wang AY, Lui SF, Leung CB, Yu AW. Comparison of clinical outcome and ease of handling in two double-bag systems in continuous ambulatory peritoneal dialysis - a prospective randomized controlled multi-center study. Am J Kidney Dis 2002; 40: 373-380 |
| 2. | Li PK, Ho KK, Szeto CC, Yu LM, Lai FM. Prognostic indicators of IgA nephropathy in Chinese £µV clinical and pathological perspectives. Nephrol Dial Transplant 2002; 17: 64-69 |
| 3. | Li PK, Chow KM, Wong TY, Leung CB, Szeto CC. Effects of an angiotensin converting enzyme inhibitor on residual renal function in patients receiving peritoneal dialysis: a prospective randomized study. Ann Intern Med 2003; 139: 105-112 |
| 4. | Szeto CC, Wong TY, Chow KM, Leung CB, Li PK. Oral sodium bicarbonate for the treatment of metabolic acidosis in peritoneal dialysis patients £µV a randomized placebo-control trial. J Am Soc Nephrol 2003; 14: 2119-2126. |
| 5. | Chow KM, Szeto CC, Wong TY, Leung CB, Li PK. Risk factors of thiazide-induced hyponatraemia. Q J Med 2003; 96: 911-917 |
| 6. | Chan RW, Tam LS, Li EK, Lai FM, Chow KM, Lai KB, Li PK, Szeto CC. Inflammatory cytokine gene expression in the urinary sediment of lupus nephritis patients. Arthritis Rheum 2003; 48: 1326-1331 |
| 7. | Szeto CC, Chow KM, Poon PY, Szeto CY, Wong TY, Li PK. Genetic polymorphism of VEGF: impact on longitudinal change of peritoneal transport and survival of PD patients. Kidney Int 2004; 65: 1947-1955 |
| 8. | Kwan BC, Leung CB, Szeto CC, Wong VW, Cheng YL, Yu AW, Li PK. Severe acute respiratory syndrome (SARS) in dialysis patients. J Am Soc Nephrol 2004; 15: 1883-1888 |
| 9. | Chan RW, Lai FM, Li EK, Tam LS, Wong TY, Szeto CY, Li PK, Szeto CC. Messenger RNA expression of chemokine and fibrosing factor in the urinary sediment of patients with lupus nephritis. Arthritis Rheum 2004; 50: 2882-2890 |
| 10. | Leung CB, Szeto CC, Ho CS, Law WK, Lam CW, Li PK. Pharmacokinetic Advantages of Two-Hour Post-Dose Cyclosporin A Level for the Therapeutic Drug Monitoring in Stable Chinese Kidney Transplant Recipients. Nephron Clin Pract 2005; 99: c68-c72 |
