Division of Clinical Pharmacology
Head of Division: Professor Brian Tomlinson
Members:
Professor Juliana CN Chan, Professor Thomas YK Chan,  Professor Clive S Cockram (Professor of Medicine, Division of Endocrinology and Diabetes)
Lecturer:
Dr. Maggie CY Ng
Honorary Research Associate
Dr. Irene W Lan, Dr. Zoe SK Lee
Research Nurse
Cherry KP Chiu, Evelyn YM Chow, Karen SY Wong
Other research staff
Theresa FP Leung, Jennifier YF Wu (Honorary HA Parmacist & Part-time MPhil student)
Laboratory Staff
Vincent KL Lam, Emily WM Poon, Nancy YL Wong
Full-time PhD
Yu-Jing Fang, Wilson YS Leung (Honorary HA Pharmacist), Ying Wang
Part-time PhD
Grace MC Chan (HA Pharmacist), Christopher WK Lai (Radiographer), Tak K Leung (Nuclear Medicine), Shirley LY Xu (Centre For Clinical Trials & Epidemiological Research)
Full-time MPhil
David Q Chen, Tanya TW Chu
Part-time MPhil
Candy KL Chong (Pharmacist), Hin-chung Chu (Chinese Medicinal Material Research Centre), Carmen L Sephton (Hong Kong Institue of Biotechnology)
Administrative Staff
Sin-wah Cheng, Charmaine SM Lee
Facilities
Drug and Poisons Information Bureau
Clinical Pharmacology Studies Unit
Research Interests
1.	Clinical Trials and Toxicology of Western and Chinese Traditional Medicines.
2.	Gene-gene and gene-environmental interactions in the pathogenesis of obesity and the metabolic syndrome in Chinese.
3.	Ethnic differences in the pharmacokinetics and pharmacodynamics of western medicines and their therapeutic use in patients with the metabolic syndrome.
4.	Quality assurance of the delivery of pharmaceutical care and its cost-effectiveness.
5.	Clinical pharmacy with particular emphasis on drug utilisation surveys and the pharmacist's role in the promotion of evidence based medicine.
Selected Publications
1.	Thomas, G. N., J. A. Critchley, B. Tomlinson, Z. S. Lee, R. P. Young, C. S. Cockram, and J. C. Chan. "Albuminuria and the Renin-angiotensin System Gene Polymorphisms in Type-2 Diabetic and Normoglycaemic Hypertensive Chinese." Clinical Nephrology 2001;55: 7-15.
2.	Chan, T. Y., J. A. Critchley, C. S. Ho, B. Tomlinson, J. C. Chan, E. W. Poon, Z. S. Lee, and L. A. Critchley. "Swaminathan R. Renal Kallikrein-kinin System, but Not Renal Dopamine System, Mediates the Natriuretic Response to Intravenous Saline Infusion in Healthy Chinese Subjects." J Auton Pharmacol. 2000;20:37-45.
3.	Lee, S. C., Y. B. Pu, G. N. Thomas, Z. S. Lee, B. Tomlinson, C. S. Cockram, J. A. Critchley, and J. C. Chan. "Tumor Necrosis Factor Alpha Gene G-308A Polymorphism in the Metabolic Syndrome." Metabolism 2000;49: 1021-1024.
4.	Thomas, G. N., B. Tomlinson, J. A. Critchley. "Modulation of Blood Pressure and Obesity with the Dopamine D2 Receptor Gene TaqI Polymorphism." Hypertension 2000;36: 177-182.
5.	Ng, M. C., J. K. Li, W. Y. So, J. A. Critchley, C. S. Cockram, G. I. Bell, and J. C. Chan. "Nature or Nurture: An Insightful Illustration from a Chinese Family with Hepatocyte Nuclear Factor-1 Alpha Diabetes." Diabetologia 2000;43: 816-818.
6.	Critchley, J. A., Y. Zhang, C. C. Suthisisang, T. Y. Chan, and B. Tomlinson. "Alternative Therapies and Medical Science: Designing Clinical Trials of Alternative/Complementary Medicines - Is Evidence-Based Traditional Chinese Medicine Attainable?" J Clin Pharmacol 2000; 40:462-467.
7.	Tomlinson B., T. Y. Chan, J. C. Chan, J. A. Critchley, and P. P. But. "Toxicity of Complementary Therapies: An Eastern Perspective." J Clin Pharmacol. 2000;40: 451-456.
8.	Chan, J. C., G. T. Ko, D. H. Leung, R. C. Cheung, M. Y. Cheung, W. Y. So, R. Swaminathan, M. G. Nicholls, J. A. Critchley, and C. S. Cockram. "Long-term Effects of Angiotensin - Converting Enzyme Inhibition and Metabolic Control in Hypertensive Type 2 Diabetic Patients." Kidney Int. 2000;57:590-600.
9.	Lee, Z. S., J. C. Chan, V. T. Yeung, C. C. Chow, M. S. Lau, G. T. Ko, J. K. Li, C. S. Cockram, and J. A. Critchley. "Plasma Insulin, Growth Hormone, Cortisol, and Central Obesity among Young Chinese Type 2 Diabetic Patients." Diabetes Care 1999;22: 1450-1457.
10.	Anderson, P. J., J. C. Chan, Y. L. Chan, B. Tomlinson, R. P. Young, Z. S. Lee, K. K. Lee, C. Metreweli, C. S. Cockram, and J. A. Critchley. "Visceral Fat and Cardiovascular Risk Factors in Chinese NIDDM Patients." Diabetes Care 1997;20: 1854-1858.